Useful LDN Information

[sw8689]

Hi all, I'm considering ldn after a 7 year stable period following mitoxantrone. My MS is now active after a car accident I was in 18 months ago..

So I'm back researching next steps. It seems there has been a lot of research done in the last 6-8 years that support its efficacy, on pain management and the inflammatory process.

A few questions, first, if I have it prescribed at 4.5 mg and made up at a compounding pharmacy, I it pretty straight forward if the pharmacy is a reputable one, or is there something special that needs to be done that is specialized?

Second, using ldn in MS, are we using it to reduce inflammation, pain, and increase energy? That is what I'm looking for.
If it is also used as a disease modifier great, but I think I will need a few more rounds of mito to stop this one in its tracks.

Ps..Carrie , pls don't take ldn or any other supplement or drug not approved by your physician while pregnant. We just don't know enough yet about it to take the chance.

[Myoak]

Hi SW,
Sorry it has taken so long to address your questions but I’m sure if you have investigated the links at the beginning of this thread you already have most of the answers.

There are just a couple comments I would make.
LDN is used primarily to halt or slow disease progression, especially in MS, as evidenced by the results of a 2008 Italian study using LDN in PPMS patients. Only one patient on LDN suffered disease progression during that study.

In human trials since 2011 LDN has proven extremely successful in treating Crohn’s Disease in children and adults. Also, LDN prevented the onset of AIDS in 71% of HIV+ patients in a peer reviewed MALI trial.

LDN does not directly affect any disease; it affects the immune system which can fight many diseases which is unregulated as a result of using LDN. A properly working immune system is nature’s way of fighting disease and keeping us healthy!!! That is why so many people are excited about the future prospects of LDN.

Unfortunately, it is a generic med and very inexpensive so no drug company wants to fund large studies and create a competitor for their profitable meds. I just read an article which said that Aubagio is the cheapest MS med at $45,000 per year. I don’t know about that but I do know some are paying $75 for a 3 month supply of LDN.

Let’s not kid ourselves, no one is going studies for a med which will never allow them to recoup Phase 3 trial costs and become an alternative to profitable expensive meds.

Lastly, I wanted to provide a couple links to a fertility doctor who uses LDN in his practice since Carrie asked. Most doctors are absolutely clueless about LDN so you have to dig into research on your own. But there is a lot available if you look. Anyway, here is the fertility doctor link, Carrie.

Dr. Phil Boyle
http://www.youtube.com/watch?v=zS8RdcvPMJY
http://www.youtube.com/watch?v=IdDq9NcF7Tk

[knuckle]

Originally Posted by Myoak

Unfortunately, it is a generic med and very inexpensive so no drug company wants to fund large studies and create a competitor for their profitable meds.

This is about to change.

A company named "TNI Biotech" will be initiating a clinical trial for LDN and SPMS next year.

Here's their website:

http://www.tnibiotech.com/

Also, there will be a LDN conference this October 5th outside Chicago at Harper College. More details to come...

[Myoak]

My apology for writing a confusing sentence in my last post, I meant to say the immune system is “up regulated” as a result of using LDN, not unregulated. A properly functioning immune system is better able to resist disease. That is key to understanding why LDN is effective in several different diseases.

Great news about the SPMS trial using LDN as a treatment! Pretty strange the MS society would not have found a way to do so years ago. Thank God for TNI Biotech, I think I’ll send them a donation.

Keep us posted on the October 5 conference at Harper College, knuckle, and thank you!

[knuckle]

Originally Posted by Myoak

Pretty strange the MS society would not have found a way to do so years ago.

Not really. The NMSS has always resisted LDN.

I'll post the conference registration website pretty soon.

TNI Biotech is building a factory in Nicaragua to produce a billion doses of LDN a year for primary distribution in Asia and Africa. They don't have to go through 10 years of FDA trials like the US does.

[knuckle]

The LDN 2013 AIIC Conference is a charity event organised by the LDN Research Trust, which is being held at Harper College, Palatine Illinois on 5th October 2013.

The conference reviews, compares and contrasts the most recent data and treatments for a variety of Auto-Immune and Immuno-modulated Conditions



**registration website removed by moderator**

[knuckle]

ok...go to "LDN 2013 dot com"