Just started with Rebif, currently on week 2. I have to say I am loving this Rebismart device...what could be easier?! I am having site reactions though, even on this low dose. I am wondering if that dissipates over time as your body adjust to the drug, or if I will forever be covered in red spots? I am also set at the deepest needle depth setting, but am noticing some medication bubbling out after injection. Does anyone have any tips or advice? Momentum helped me reset the injection speed, so hoping this helps. I discontinued Copaxone because of the site reactions, I am really hoping Rebif works for me as this delivery system is AWESOME. No other side effect yet, other than the red spots.