I am having to pee like every 10 minutes since I started Rebif. It doesn't burn I just really have to go and I go alot (empty bladder - didn't realize I had that much liquid in me)!!. Anyone have this problem. also I have the very bad headaches and monster fatigue even worse than before. I went to Patient First to see if it was a uti but it's didn't come up that it was a bad one but they gave me Ceftin which the doctor said would clear up anything within 24 hours. It's been 3 days and NOTHING has changed.